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Isaac Jesayes Spier, birth 17 Sep 1806 Harlingen, Friesland, Nederland, son of Jesayes Levy Spier and Beeltje-Beletje Izaaks de Vries
Married 29 May 1828 Harlingen, Friesland, Nederland to: Eva Salomon Swaap, birth 1805 Amsterdam, Noord-Holland, Nederland, daughter of Salomon Zadok Swaap and Annaatje Wolf |
| 1) Jesayes Spier, birth 6 May 1830 Harlingen, Friesland, Nederland |
| 2) Jantje Spier, birth 14 Jun 1832 Harlingen, Friesland, Nederland |